Curis, Inc. (CRIS) - Winst- en verliesrekening per kwartaal

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CRIS
Financiële Gegevens

3.93 (USD) • At close November 13, 2024

Overzicht | Financiële gegevens

Cijfers zijn in miljoenen (behalve de cijfers per aandeel en de ratio's) USD.

	2024 Q2	2024 Q1	2023 Q4	2023 Q3	2023 Q2	2023 Q1	2022 Q4	2022 Q3	2022 Q2	2022 Q1	2021 Q4	2021 Q3	2021 Q2	2021 Q1	2020 Q4	2020 Q3	2020 Q2	2020 Q1	2019 Q4	2019 Q3	2019 Q2	2019 Q1	2018 Q4	2018 Q3	2018 Q2	2018 Q1	2017 Q4	2017 Q3	2017 Q2	2017 Q1	2016 Q4	2016 Q3	2016 Q2	2016 Q1	2015 Q4	2015 Q3	2015 Q2	2015 Q1	2014 Q4	2014 Q3	2014 Q2	2014 Q1	2013 Q4	2013 Q3	2013 Q2	2013 Q1	2012 Q4	2012 Q3	2012 Q2	2012 Q1	2011 Q4	2011 Q3	2011 Q2	2011 Q1	2010 Q4	2010 Q3	2010 Q2	2010 Q1	2009 Q4	2009 Q3	2009 Q2	2009 Q1	2008 Q4	2008 Q3	2008 Q2	2008 Q1	2007 Q4	2007 Q3	2007 Q2	2007 Q1	2006 Q4	2006 Q3	2006 Q2	2006 Q1	2005 Q4	2005 Q3	2005 Q2	2005 Q1	2004 Q4	2004 Q3	2004 Q2	2004 Q1	2003 Q4	2003 Q3	2003 Q2	2003 Q1	2002 Q4	2002 Q3	2002 Q2	2002 Q1	2001 Q4	2001 Q3	2001 Q2	2001 Q1	2000 Q4	2000 Q3
Omzet Numbers are in millions	2.546	2.086	2.696	2.833	2.197	2.297	2.887	2.825	2.393	2.057	3.135	3.039	2.286	2.189	3.024	2.742	2.36	2.709	3.287	2.856	2.094	1.767	2.755	2.847	2.358	2.468	3.262	2.444	2.061	2.131	2.362	1.759	1.68	1.726	2.093	2.045	2.083	1.658	1.993	1.765	4.801	1.285	1.524	7.202	5.404	0.871	1.686	0.578	4.352	10.356	14.089	0.147	0.393	0.134	0.1	3.242	0.099	12.558	1.724	0.765	0.063	6.037	3.105	0.087	3.108	2.068	11.485	1.312	1.229	2.363	4.34	4.629	3.105	2.865	3.199	1.815	1.521	2.772	1.491	1.486	1.12	0.856	0.755	9.309	0.549	0.435	17.82	0.222	0.19	0.159	0.347	0.288	0.203	2.743	0.253	0.066
Kosten van de omzet Numbers are in millions	0.012	0.465	0.158	0.06	0.074	0.024	0.071	0.062	0.042	0.082	0.157	0.151	0.116	0.109	0.151	0.135	0.122	0.125	0.161	0.145	0.089	0.108	0.146	0.154	0.134	0.129	0.165	0.124	0.096	0.111	0.121	0.094	0.095	0.089	0.103	0.116	0.103	0.084	0.093	0.089	0.092	0.065	0.07	0.054	0.04	0.033	0.028	0.022	0.013	0.114	0	0	0	0	0	0	0	0	0	0	0	0	0	-0	0	0	0	0	0	0	1.728	0.355	0.546	0.826	3.305	0.019	0.019	3.305	0	0.019	0.019	0.019	0	0.019	0.019	0.019	5.337	0.06	0	0	0	0	0	-6.447	-10.485	-0.782
Brutowinst Numbers are in millions	2.534	1.621	2.538	2.773	2.123	2.273	2.816	2.763	2.351	1.975	2.978	2.888	2.17	2.08	2.873	2.607	2.238	2.584	3.126	2.711	2.005	1.659	2.609	2.693	2.224	2.339	3.097	2.32	1.965	2.02	2.241	1.665	1.585	1.637	1.99	1.929	1.98	1.574	1.899	1.676	4.709	1.219	1.454	7.148	5.364	0.838	1.658	0.555	4.339	10.243	14.089	0.147	0.393	0.134	0.1	3.242	0.099	12.558	1.724	0.765	0.063	6.037	3.105	0.087	3.108	2.068	11.485	1.312	1.229	2.363	2.612	4.273	2.559	2.038	-0.105	1.796	1.502	-0.533	1.491	1.467	1.101	0.837	0.755	9.29	0.53	0.417	12.483	0.162	0.19	0.159	0.347	0.288	0.203	9.19	10.738	0.847
Brutowinstmarge Numbers are in millions	0.995	0.777	0.941	0.979	0.966	0.99	0.975	0.978	0.982	0.96	0.95	0.95	0.949	0.95	0.95	0.951	0.948	0.954	0.951	0.949	0.957	0.939	0.947	0.946	0.943	0.948	0.949	0.949	0.953	0.948	0.949	0.947	0.943	0.949	0.951	0.943	0.951	0.949	0.953	0.949	0.981	0.949	0.954	0.993	0.993	0.962	0.983	0.961	0.997	0.989	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	1	0.602	0.923	0.824	0.712	-0.033	0.99	0.988	-0.192	1	0.987	0.983	0.978	1	0.998	0.966	0.957	0.701	0.73	1	1	1	1	1	3.35	42.398	12.849
Onderzoek- en ontwikkelingskosten Numbers are in millions	10.254	9.617	9.964	10.38	10.012	9.14	8.706	10.813	12.323	11.435	10.772	8.602	8.753	6.757	5.609	4.705	5.282	7.473	7.461	3.721	5.62	2.472	4.713	2.544	3.213	4.794	4.356	10.602	7.983	10.404	9.159	4.403	6.832	4.817	12.041	3.831	5.938	4.719	3.479	3.509	3.22	2.954	2.961	4.171	3.167	2.628	2.707	3.042	4.5	5.242	4.448	3.042	3.144	3.058	3.652	3.009	2.245	2.468	2.44	2.296	2.281	2.916	3.55	3	3.201	3.476	5.233	3.203	3.047	3.296	3.595	3.669	3.84	3.485	3.057	3.821	3.687	3.116	2.985	2.947	2.83	2.808	3.858	3.036	3.593	2.914	2.436	2.884	3.903	4.835	6.169	6.902	7.893	8.109	7.351	6.056
Algemene en administratieve kosten Numbers are in millions	4.792	4.891	4.877	4.761	4.249	4.76	4.33	4.556	5.089	5.673	4.773	4.334	4.068	4.123	3.539	2.613	2.386	3.593	2.999	4.313	2.526	4.745	3.044	6.566	6.871	7.453	5.869	6.189	7.091	6.669	3.845	7.062	5.433	5.627	3.195	2.941	3.411	3.529	3.231	2.919	3.034	3.019	2.976	2.847	2.904	2.567	2.883	2.474	2.265	2.801	2.076	1.921	1.868	2.407	2.059	1.999	1.78	4.426	2.011	2.566	2.03	2.095	1.858	1.862	2.125	2.415	2.442	2.231	2.359	2.952	2.224	2.302	2.962	2.886	1.949	1.833	2.684	1.648	1.608	2.48	2.628	1.915	1.811	1.729	2.148	1.798	2.654	2	2.257	3.409	13.14	2.456	6.34	6.414	6.858	13.397
Verkoop- en marketingkosten Numbers are in millions	0	-0.418	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0
Verkoop-, algemene en administratieve kosten Numbers are in millions	4.792	4.473	4.877	4.761	4.249	4.76	4.33	4.556	5.089	5.673	4.773	4.334	4.068	4.123	3.539	2.613	2.386	3.593	2.999	4.313	2.526	4.745	3.044	6.566	6.871	7.453	5.869	6.189	7.091	6.669	3.845	7.062	5.433	5.627	3.195	2.941	3.411	3.529	3.231	2.919	3.034	3.019	2.976	2.847	2.904	2.567	2.883	2.474	2.265	2.801	2.076	1.921	1.868	2.407	2.059	1.999	1.78	4.426	2.011	2.566	2.03	2.095	1.858	1.862	2.125	2.415	2.442	2.231	2.359	2.952	2.224	2.302	2.962	2.886	1.949	1.833	2.684	1.648	1.608	2.48	2.628	1.915	1.811	1.729	2.148	1.798	2.654	2	2.257	3.409	13.14	2.456	6.34	6.414	6.858	13.397
Overige kosten Numbers are in millions	0	0.078	0.01	0.06	0.074	0.068	-1.109	-1.023	0	0	0	0	0.89	0	0	0	0.001	0.021	-0.042	0.02	0	-3.495	0	4.917	6.415	8.26	45.047	13.35	11.214	-0.103	49.862	24.712	0	0	0	0	0	-0.827	0	3.687	3.306	3.142	0	4.049	2.568	-0.605	1.061	2.911	4.402	5.156	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	0	1.057	0.912	0	1.065	0.077	0	0	0.368	0.389	0.302	0	2.969	3.763	2.791	84.035	3.398	0	0	0	0	0	0	0	0
Bedrijfskosten Numbers are in millions	15.058	14.09	14.841	15.201	14.261	13.9	13.036	15.369	17.412	17.108	15.545	12.936	12.821	10.88	9.148	7.318	7.668	11.066	10.46	8.034	8.146	7.217	7.757	9.11	10.084	12.247	10.225	16.791	15.074	17.073	13.004	11.465	12.265	10.444	15.236	6.772	9.349	8.248	6.71	6.428	6.254	5.973	5.937	7.018	6.07	5.196	5.591	5.516	6.765	8.157	6.524	4.963	5.012	5.466	5.711	5.007	4.025	6.894	4.45	4.862	4.311	5.011	5.407	4.862	5.325	5.891	7.675	5.435	5.406	6.247	5.819	5.975	6.811	6.389	5.025	-3.857	6.39	5.849	4.612	-3.959	5.477	5.043	5.687	4.784	5.759	4.731	74.818	4.944	70.483	16.966	25.172	15.185	20.057	26.793	16.047	28.764
Bedrijfsresultaat Numbers are in millions	-12.512	-12.469	-12.199	-12.368	-12.138	-11.627	-10.22	-12.606	-15.061	-15.133	-12.567	-10.048	-10.65	-8.8	-6.275	-4.711	-5.43	-8.482	-7.334	-5.323	-6.141	-5.558	-5.148	-6.417	-7.86	-9.908	-7.128	-14.471	-13.109	-15.053	-10.763	-27.789	-10.68	-8.807	-13.246	-4.844	-7.369	-31.022	-4.811	-4.753	-1.545	-4.753	-4.483	0.13	-0.706	-4.357	-13.432	-4.961	-2.426	2.2	7.565	-4.816	-4.619	-5.332	-5.61	-1.765	-3.926	5.664	-2.726	-4.097	-4.248	1.026	-2.303	-4.776	-2.218	-3.824	3.81	-4.123	-4.177	-3.884	0.249	-1.701	-4.252	-4.351	-1.826	5.672	-4.869	-5.316	-3.121	5.445	-4.357	-4.188	-4.932	4.525	-5.21	-4.295	-60.488	-4.722	-70.294	-16.807	-24.825	-14.898	-19.854	-17.603	-5.309	-27.916
Bedrijfsresultaat ratio Numbers are in millions	-4.914	-5.977	-4.525	-4.366	-5.525	-5.062	-3.54	-4.462	-6.294	-7.357	-4.009	-3.306	-4.659	-4.02	-2.075	-1.718	-2.301	-3.131	-2.231	-1.864	-2.933	-3.145	-1.869	-2.254	-3.333	-4.015	-2.185	-5.921	-6.361	-7.064	-4.557	-15.798	-6.357	-5.103	-6.33	-2.369	-3.539	-18.706	-2.414	-2.693	-0.322	-3.7	-2.941	0.018	-0.131	-5	-7.965	-8.586	-0.558	0.212	0.537	-32.737	-11.757	-39.931	-55.943	-0.544	-39.809	0.451	-1.581	-5.354	-67.143	0.17	-0.742	-55.068	-0.714	-1.849	0.332	-3.142	-3.4	-1.644	0.057	-0.368	-1.369	-1.519	-0.571	3.125	-3.202	-1.918	-2.094	3.664	-3.89	-4.893	-6.532	0.486	-9.491	-9.866	-3.394	-21.235	-370.742	-105.951	-71.587	-51.743	-97.978	-6.417	-20.963	-423.263
Totaal overige inkomsten en kosten netto Numbers are in millions	0.709	0.593	0.487	0.187	0.177	0.068	-1.109	-0.688	-0.879	-0.976	-1.053	-1.003	-0.188	-1.127	-1.242	-1.263	-1.278	-1.227	-1.274	-1.113	-1.072	-4.326	-0.793	-0.806	-0.804	-0.839	-0.9	-0.986	-0.981	-0.689	-0.572	-0.556	-0.61	-0.634	-0.215	-0.699	-0.759	-0.827	-0.879	-0.827	-0.351	-0.811	0.285	-1.998	-0.588	-0.605	2,197.713	1.576	-0.46	0.026	-17.424	0.61	-0.295	-1.468	1.175	0.25	3.926	-0.88	-7.097	0.037	0.066	0.099	2.303	1.057	0.253	0.393	1,398.134	0.404	0.18	0.344	1,215.317	0.165	0.328	0.302	1.826	0.226	0.377	0.203	3.121	-5.445	0.055	0.15	4.932	0.025	0.262	0.006	-21.827	-1.031	-64.963	-9.675	6.501	-13.628	0	0	-14.336	-295.354
Inkomen voor belasting Numbers are in millions	-11.803	-11.876	-11.712	-12.181	-11.961	-11.559	-11.329	-13.294	-15.94	-16.109	-13.62	-11.051	-10.839	-9.927	-7.517	-5.974	-6.708	-9.709	-8.609	-6.436	-7.213	-9.884	-5.941	-7.223	-8.664	-10.747	-8.028	-15.457	-14.09	-15.742	-11.335	-28.345	-11.29	-9.441	-13.461	-5.543	-8.129	-31.848	-5.689	-5.58	-1.896	-5.564	-4.198	-1.868	-1.294	-4.962	-12.371	-3.385	-2.886	2.226	-9.859	-4.207	-4.914	-6.8	-4.435	-1.515	-2,097.987	4.784	-9.823	-4.06	-4.181	1.125	-12,123.098	-3.718	-1.965	-3.431	-6,964.243	-3.718	-3.998	-3.541	-8,829.322	-1.537	-3.924	-4.049	-14,855.172	-3.251	-4.858	-5.381	-13,904.274	-3.906	-4.301	-4.038	-11,623.252	4.55	-4.948	-4.29	-82.315	-5.753	-135.256	-26.482	-18.324	-28.525	0	0	-19.645	-323.27
Inkomen voor belasting ratio Numbers are in millions	-4.636	-5.693	-4.344	-4.3	-5.444	-5.032	-3.924	-4.706	-6.661	-7.831	-4.344	-3.636	-4.741	-4.535	-2.486	-2.179	-2.842	-3.584	-2.619	-2.254	-3.445	-5.594	-2.156	-2.537	-3.674	-4.355	-2.461	-6.324	-6.836	-7.387	-4.799	-16.114	-6.72	-5.47	-6.433	-2.71	-3.903	-19.205	-2.855	-3.161	-0.395	-4.331	-2.754	-0.259	-0.239	-5.694	-7.336	-5.859	-0.663	0.215	-0.7	-28.592	-12.508	-50.923	-44.223	-0.467	-21,270.424	0.381	-5.697	-5.305	-66.095	0.186	-3,905.004	-42.877	-0.632	-1.659	-606.386	-2.834	-3.253	-1.499	-2,034.332	-0.332	-1.264	-1.413	-4,643.121	-1.791	-3.195	-1.941	-9,328.503	-2.628	-3.84	-4.718	-15,393.099	0.489	-9.013	-9.854	-4.619	-25.872	-713.366	-166.94	-52.84	-99.076	0	0	-77.568	-4,901.375
Belastingkosten Numbers are in millions	0	0.375	-0.747	-0.063	0.815	-0.068	1.109	0.688	0.879	0.976	1.106	0.054	2.025	0.046	-0.024	0.003	1.285	1.319	1.264	1.323	0.203	-2.556	0.104	0.166	0.189	0.186	0.182	0.123	0.138	0.553	-0	0.657	0.119	0.105	-0	0.128	0.821	24.306	-0.001	0.935	0.95	0.951	0	0.928	0.924	-0.034	-4.046	-1.576	0.43	-0.056	-15.921	-0.641	0.271	1.468	1.171	-0.25	-1.828	0.88	-7.117	0	0	0	-9.967	-0.204	-0.253	-0.393	-11.257	-0.404	-0.18	-0.344	-9.51	-0.165	0	0	-13.419	9.529	0	-1.268	-12.245	9.351	-0.055	-0.15	-4.688	-0.025	-0.262	-0.006	-94.566	0.054	-0.379	-0.149	-9.327	0.93	-0.577	6.028	13.816	294.953
Nettowinst Numbers are in millions	-11.803	-11.876	-11.78	-12.181	-11.961	-11.491	-12.438	-13.982	-16.819	-17.085	-13.62	-11.051	-10.838	-9.927	-7.517	-5.974	-6.708	-9.709	-8.609	-6.436	-7.213	-9.884	-5.941	-7.223	-8.664	-10.747	-8.028	-15.457	-14.09	-15.742	-11.335	-28.345	-11.29	-9.441	-13.461	-5.543	-8.129	-31.848	-5.689	-5.58	-1.896	-5.564	-4.198	-1.868	-1.294	-4.962	-12.371	-3.385	-2.886	2.226	6.062	-4.207	-4.914	-6.8	-5.607	-1.515	-2.098	4.784	-2.706	-4.06	-4.181	1.125	-2.156	-4.571	-1.965	-3.431	4.292	-3.718	-3.998	-3.541	0.68	-1.537	-3.924	-4.049	-1.437	-3.631	-4.675	-5.113	-1.659	-3.906	-4.301	-4.038	-6.936	4.55	-4.948	-4.29	12.251	-5.753	-70.993	-17.82	-16.254	-28.525	-19.277	-17.807	-19.125	-322.869
Nettowinstmarge Numbers are in millions	-4.636	-5.693	-4.369	-4.3	-5.444	-5.003	-4.308	-4.949	-7.028	-8.306	-4.344	-3.636	-4.741	-4.535	-2.486	-2.179	-2.842	-3.584	-2.619	-2.254	-3.445	-5.594	-2.156	-2.537	-3.674	-4.355	-2.461	-6.324	-6.836	-7.387	-4.799	-16.114	-6.72	-5.47	-6.433	-2.711	-3.903	-19.205	-2.855	-3.162	-0.395	-4.331	-2.754	-0.259	-0.239	-5.694	-7.336	-5.859	-0.663	0.215	0.43	-28.592	-12.508	-50.923	-55.907	-0.467	-21.27	0.381	-1.569	-5.305	-66.095	0.186	-0.695	-52.714	-0.632	-1.659	0.374	-2.834	-3.253	-1.499	0.157	-0.332	-1.264	-1.413	-0.449	-2	-3.074	-1.845	-1.113	-2.628	-3.84	-4.718	-9.185	0.489	-9.013	-9.854	0.687	-25.872	-374.431	-112.336	-46.87	-99.076	-95.13	-6.492	-75.513	-4,895.296
WPA (Winst Per Aandeel) Numbers are in millions	-2.03	-2.05	-2.04	-2.13	-2.47	-2.38	-2.58	-2.98	-3.67	-3.73	-2.97	-2.41	-2.37	-2.17	-2.27	-2.19	-3.39	-5.64	-5.18	-3.88	-4.35	-5.96	-3.59	-4.36	-5.23	-6.5	-0.24	-10.55	-9.8	-11.09	-8.06	-21.46	-8.73	-7.32	-10.48	-4.32	-6.33	-29.51	-6.61	-6.49	-2.21	-6.48	-4.9	-2.27	-1.59	-6.2	-15.47	-4.25	-3.65	3	8	-5.5	-6.43	-8.97	-0.37	-2	-2.77	7	-0.2	-6.13	-6.57	2	-0.17	-7.21	-3.1	-5.42	0.45	-6.46	-8.09	-7.17	0.05	-3.13	-8	-8.29	-0.15	-7.54	-9.75	-10.69	-0.18	-9.38	-10.37	-9.82	-0.86	12	-14.77	-13.52	1.75	-17.66	-219.56	-55.12	-2.48	-88.76	-61.08	-56.65	-3.05	-1,519.38
Verwaterde WPA Numbers are in millions	-2.03	-2.05	-2.04	-2.13	-2.47	-2.38	-2.58	-2.98	-3.67	-3.73	-2.97	-2.41	-2.37	-2.17	-2.27	-2.19	-3.39	-5.64	-5.18	-3.88	-4.35	-5.96	-3.59	-4.36	-5.23	-6.5	-0.24	-10.55	-9.8	-11.09	-8.06	-21.46	-8.73	-7.32	-10.48	-4.32	-6.33	-29.51	-6.61	-6.49	-2.21	-6.48	-4.9	-2.27	-1.59	-6.2	-15.47	-4.25	-3.65	3	7	-5.5	-6.43	-8.97	-0.37	-2	-2.77	6	-0.2	-6.13	-6.57	2	-0.17	-7.21	-3.1	-5.42	0.45	-6.46	-8.09	-7.17	0.05	-3.13	-8	-8.29	-0.15	-7.54	-9.75	-10.69	-0.18	-9.38	-10.37	-9.82	-0.86	11	-14.77	-13.52	1.75	-17.66	-219.56	-55.12	-2.48	-88.76	-61.08	-56.65	-3.05	-1,519.38
EBITDA Numbers are in millions	-12.512	-12.051	-11.47	-12.368	-12.138	-11.627	-9.268	-12.606	-14.855	-15.017	-12.264	-9.958	-9.456	-8.711	-6.242	-4.656	-5.385	-8.386	-7.246	-5.103	-5.874	-8.91	-4.967	-6.211	-7.625	-9.669	-6.887	-14.285	-12.913	-15.031	-10.631	-27.637	-10.505	-8.807	-12.635	-4.844	-7.369	-31.022	-4.735	-4.606	-1.545	-4.576	-3.189	0.13	-0.706	-4.357	-10.99	-4.961	-2.426	2.174	7.596	-4.785	-4.595	-5.311	-5.446	-1.604	-3.746	5.664	-2.541	-3.91	-4.06	1.026	-2.067	-4.522	-1.964	-3.568	4.065	-3.863	-3.866	-3.409	0.688	-1.389	-3.913	-4.006	-1.536	-3.179	-4.869	-5.369	-2.935	5.713	-4.056	-3.867	-4.603	4.525	-4.813	-3.881	-56.315	-4.247	-69.742	-16.141	-17.517	-8.52	-13.359	-13.65	-3.472	-18.605
EBITDA ratio Numbers are in millions	-4.914	-5.777	-4.905	-4.366	-5.125	-5.062	-3.54	-4.322	-6.208	-7.3	-3.992	-3.277	-4.227	-3.979	-2.074	-1.698	-2.282	-3.096	-2.213	-1.787	-2.82	-5.042	-1.817	-2.182	-3.234	-3.918	-2.111	-5.845	-6.265	-7.053	-4.523	-5.485	-6.253	-5.022	-6.056	-2.286	-3.498	10.658	-2.396	-2.649	-0.305	-3.634	-2.911	0.024	-0.124	-5	3.301	-11.201	-0.452	0.21	0.644	-36.882	-11.006	-28.53	-53.968	-0.559	-56.2	0.538	-1.474	-5.109	-64.171	0.202	-0.666	-52.16	-0.633	-1.728	0.354	-2.943	-3.045	-1.448	0.153	-0.262	-1.26	-1.398	-0.511	3.289	-3.063	-2.233	-2.881	3.818	-3.657	-4.346	-3.795	0.522	-9.246	-8.928	-4.223	-18.619	-30.893	-48.087	-71.439	-26.36	-65.927	-1.944	42.897	4,196.019

Curis, Inc.

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NASDAQ:CRIS